AKLIEF (Trifarotene 50 mcg/g) topical cream is indicated for the topical treatment of acne vulgaris of the face and/or trunk in patients 12 years of age and older. The main ingredient is trifarotene, a topical retinoid for use on your trunk (chest, back, and shoulders) as well as on your face. AKLIEF unclogs pores, clearing existing acne and preventing new acne from forming. It also reduces inflammation.